| Time | Status | Match | FT | H1 | Stats |
| 01/04/2022 18:00 |
(FT) | Leixoes[7] Penafiel[9] |
0 1 |
0 0 |
MF | ME |
| 02/04/2022 11:00 |
(FT) | CD Mafra[8] SL Benfica B[3] |
2 1 |
2 0 |
MF | ME |
| 02/04/2022 14:00 |
(FT) | Feirense[5] Academico Viseu[15] |
2 1 |
1 0 |
MF | ME |
| 02/04/2022 20:00 |
(FT) | Rio Ave[1] Clube Desportivo Trofense[14] |
1 0 |
1 0 |
MF | ME |
| 03/04/2022 11:00 |
(FT) | Academica Coimbra[18] Casa Pia Ac[2] |
0 2 |
0 1 |
MF | ME |
| 03/04/2022 14:00 |
(FT) | Chaves[4] CD Nacional[6] |
2 0 |
1 0 |
MF | ME |
| 03/04/2022 14:00 |
(FT) | SC Farense[10] SC Covilha[16] |
1 0 |
0 0 |
MF | ME |
| 03/04/2022 19:00 |
(FT) | Amadora[12] Vilafranquense[13] |
0 1 |
0 1 |
MF | ME |
| 04/04/2022 18:00 |
(FT) | Varzim[17] Porto B[11] |
2 1 |
1 1 |
MF | ME |