| Time | Status | Match | FT | H1 | Stats |
| 11/03/2022 18:00 |
(FT) | Academica Coimbra[18] SL Benfica B[3] |
3 4 |
0 1 |
MF | ME |
| 11/03/2022 18:00 |
(FT) | Varzim[17] Academico Viseu[15] |
1 0 |
1 0 |
MF | ME |
| 12/03/2022 11:00 |
(FT) | Amadora[11] Feirense[5] |
1 2 |
1 0 |
MF | ME |
| 12/03/2022 14:00 |
(FT) | Rio Ave[2] Penafiel[8] |
2 0 |
1 0 |
MF | ME |
| 13/03/2022 11:00 |
(FT) | SC Farense[13] Porto B[9] |
2 0 |
0 0 |
MF | ME |
| 13/03/2022 14:00 |
(FT) | CD Mafra[10] CD Nacional[6] |
3 2 |
1 1 |
MF | ME |
| 13/03/2022 14:00 |
(FT) | Chaves[4] Casa Pia Ac[1] |
4 1 |
1 1 |
MF | ME |
| 13/03/2022 15:30 |
(FT) | SC Covilha[16] Clube Desportivo Trofense[14] |
2 0 |
0 0 |
MF | ME |
| 14/03/2022 19:30 |
(FT) | Leixoes[7] Vilafranquense[12] |
1 1 |
0 0 |
MF | ME |