| Time | Status | Match | FT | H1 | Stats |
| 11/02/2022 18:00 |
(FT) | Casa Pia Ac[1] Clube Desportivo Trofense[13] |
1 0 |
1 0 |
MF | ME |
| 12/02/2022 11:00 |
(FT) | CD Mafra[11] Porto B[7] |
3 2 |
2 1 |
MF | ME |
| 12/02/2022 14:00 |
(FT) | Academica Coimbra[17] Feirense[3] |
1 2 |
1 1 |
MF | ME |
| 13/02/2022 11:00 |
(FT) | CD Nacional[6] Penafiel[8] |
3 0 |
1 0 |
MF | ME |
| 13/02/2022 14:00 |
(FT) | SC Covilha[16] SL Benfica B[2] |
1 2 |
0 1 |
MF | ME |
| 13/02/2022 15:59 |
(FT) | Varzim[18] Leixoes[10] |
1 1 |
0 1 |
MF | ME |
| 13/02/2022 19:30 |
(FT) | SC Farense[15] Academico Viseu[14] |
1 1 |
1 1 |
MF | ME |
| 14/02/2022 18:00 |
(FT) | Chaves[3] Vilafranquense[12] |
1 0 |
0 0 |
MF | ME |
| 14/02/2022 18:00 |
(FT) | Rio Ave[5] Amadora[9] |
1 0 |
1 0 |
MF | ME |