| Time | Status | Match | FT | H1 | Stats |
| 26/11/2021 18:00 |
(FT) | SC Farense[15] Casa Pia Ac[3] |
0 1 |
0 1 |
MF | ME |
| 27/11/2021 11:00 |
(FT) | Chaves[12] CD Mafra[5] |
0 1 |
0 1 |
MF | ME |
| 27/11/2021 14:00 |
(FT) | Varzim[17] Penafiel[8] |
0 2 |
0 2 |
MF | ME |
| 27/11/2021 15:30 |
(FT) | Academico Viseu[9] Vilafranquense[16] |
0 0 |
0 0 |
MF | ME |
| 28/11/2021 11:00 |
(FT) | Feirense[2] Porto B[11] |
3 2 |
2 0 |
MF | ME |
| 28/11/2021 14:00 |
(FT) | Rio Ave[4] CD Nacional[6] |
1 0 |
0 0 |
MF | ME |
| 28/11/2021 15:30 |
(FT) | Leixoes[10] Clube Desportivo Trofense[14] |
1 2 |
1 1 |
MF | ME |
| 28/11/2021 19:30 |
(FT) | Academica Coimbra[18] SC Covilha[13] |
3 0 |
1 0 |
MF | ME |
| 29/11/2021 18:00 |
(FT) | Amadora[7] SL Benfica B[1] |
3 6 |
2 3 |
MF | ME |