| Time | Status | Match | FT | H1 | Stats |
| 05/03/2022 11:00 |
(FT) | Academico Viseu[14] Amadora[11] |
0 4 |
0 3 |
MF | ME |
| 05/03/2022 14:00 |
(FT) | CD Nacional[6] SC Covilha[16] |
1 1 |
0 0 |
MF | ME |
| 06/03/2022 11:00 |
(FT) | Feirense[5] Leixoes[7] |
0 1 |
0 0 |
MF | ME |
| 06/03/2022 14:00 |
(FT) | Penafiel[10] Chaves[4] |
2 1 |
0 1 |
MF | ME |
| 06/03/2022 15:30 |
(FT) | Porto B[9] Academica Coimbra[18] |
3 3 |
2 1 |
MF | ME |
| 06/03/2022 18:00 |
(FT) | SL Benfica B[2] Varzim[17] |
1 2 |
0 2 |
MF | ME |
| 06/03/2022 20:15 |
(FT) | Clube Desportivo Trofense[15] SC Farense[13] |
1 1 |
0 0 |
MF | ME |
| 07/03/2022 18:00 |
(FT) | Vilafranquense[12] Rio Ave[3] |
1 2 |
0 0 |
MF | ME |
| 08/03/2022 20:15 |
(FT) | Casa Pia Ac[1] CD Mafra[8] |
3 1 |
3 1 |
MF | ME |