| Time | Status | Match | FT | H1 | Stats |
| 18/02/2022 18:00 |
(FT) | Academico Viseu[14] Leixoes[11] |
1 2 |
0 2 |
MF | ME |
| 19/02/2022 11:00 |
(FT) | Vilafranquense[12] Academica Coimbra[17] |
2 1 |
1 1 |
MF | ME |
| 19/02/2022 14:00 |
(FT) | Casa Pia Ac[1] CD Nacional[6] |
1 0 |
1 0 |
MF | ME |
| 20/02/2022 11:00 |
(FT) | Penafiel[8] SC Covilha[16] |
1 1 |
1 1 |
MF | ME |
| 20/02/2022 14:00 |
(FT) | Feirense[4] Rio Ave[5] |
0 0 |
0 0 |
MF | ME |
| 20/02/2022 15:30 |
(FT) | Porto B[7] Chaves[3] |
0 0 |
0 0 |
MF | ME |
| 20/02/2022 19:30 |
(FT) | Clube Desportivo Trofense[13] CD Mafra[9] |
1 3 |
0 0 |
MF | ME |
| 21/02/2022 18:00 |
(FT) | SL Benfica B[2] SC Farense[14] |
3 0 |
2 0 |
MF | ME |
| 21/02/2022 19:00 |
(FT) | Amadora[10] Varzim[18] |
0 0 |
0 0 |
MF | ME |