| Time | Status | Match | FT | H1 | Stats |
| 28/01/2022 18:00 |
(FT) | SC Farense[16] Amadora[6] |
3 0 |
0 0 |
MF | ME |
| 28/01/2022 20:15 |
(FT) | Clube Desportivo Trofense[14] SL Benfica B[1] |
2 0 |
0 0 |
MF | ME |
| 30/01/2022 11:00 |
(FT) | CD Mafra[10] Academico Viseu[13] |
0 0 |
0 0 |
MF | ME |
| 30/01/2022 11:00 |
(FT) | CD Nacional[5] Porto B[8] |
1 0 |
1 0 |
MF | ME |
| 30/01/2022 12:45 |
(FT) | Rio Ave[4] Varzim[17] |
1 1 |
1 1 |
MF | ME |
| 30/01/2022 14:00 |
(FT) | Chaves[7] Feirense[3] |
3 1 |
1 0 |
MF | ME |
| 30/01/2022 15:30 |
(FT) | SC Covilha[15] Vilafranquense[12] |
1 1 |
1 1 |
MF | ME |
| 30/01/2022 17:30 |
(FT) | Academica Coimbra[18] Leixoes[11] |
1 0 |
0 0 |
MF | ME |
| 31/01/2022 17:00 |
(FT) | Casa Pia Ac[2] Penafiel[9] |
2 0 |
1 0 |
MF | ME |