| Time | Status | Match | FT | H1 | Stats |
| 17/09/2021 18:00 |
(FT) | SC Covilha[8] Penafiel[5] |
0 0 |
0 0 |
MF | ME |
| 18/09/2021 11:00 |
(FT) | Rio Ave[1] Feirense[2] |
0 4 |
0 2 |
MF | ME |
| 18/09/2021 15:30 |
(FT) | CD Mafra[4] Clube Desportivo Trofense[12] |
0 0 |
0 0 |
MF | ME |
| 19/09/2021 11:00 |
(FT) | CD Nacional[10] Casa Pia Ac[9] |
1 2 |
0 0 |
MF | ME |
| 19/09/2021 11:00 |
(FT) | SC Farense[16] SL Benfica B[3] |
2 2 |
1 2 |
MF | ME |
| 19/09/2021 14:00 |
(FT) | Chaves[11] Porto B[7] |
4 2 |
0 2 |
MF | ME |
| 20/09/2021 18:00 |
(FT) | Academica Coimbra[17] Vilafranquense[18] |
1 2 |
1 1 |
MF | ME |
| 20/09/2021 19:30 |
(FT) | Leixoes[6] Academico Viseu[14] |
1 4 |
0 1 |
MF | ME |
| 21/09/2021 18:00 |
(FT) | Varzim[15] Amadora[13] |
3 1 |
2 0 |
MF | ME |