| Time | Status | Match | FT | H1 | Stats |
| 15/01/2022 11:00 |
(FT) | Casa Pia Ac[2] Academico Viseu[14] |
0 1 |
0 1 |
MF | ME |
| 15/01/2022 15:30 |
(FT) | Penafiel[10] Vilafranquense[12] |
4 3 |
2 2 |
MF | ME |
| 16/01/2022 11:00 |
(FT) | CD Nacional[4] SL Benfica B[1] |
0 3 |
0 2 |
MF | ME |
| 17/01/2022 18:00 |
(FT) | SC Farense[16] Leixoes[13] |
0 1 |
0 1 |
MF | ME |
| 18/01/2022 18:00 |
(FT) | CD Mafra[9] Amadora[8] |
2 2 |
0 1 |
MF | ME |
| 18/01/2022 20:15 |
(FT) | SC Covilha[15] Feirense[3] |
2 2 |
0 0 |
MF | ME |
| 19/01/2022 18:00 |
(FT) | Academica Coimbra Rio Ave |
1 2 |
0 1 |
MF | ME |
| 02/02/2022 18:00 |
(FT) | Chaves[7] Varzim[17] |
1 0 |
0 0 |
MF | ME |
| 03/02/2022 18:00 |
(FT) | Clube Desportivo Trofense[11] Porto B[8] |
2 2 |
0 2 |
MF | ME |