| Time | Status | Match | FT | H1 | Stats |
| 11/12/2021 11:00 |
(FT) | Feirense[3] Penafiel[5] |
1 2 |
1 0 |
MF | ME |
| 11/12/2021 14:00 |
(FT) | Rio Ave[4] CD Mafra[7] |
1 2 |
1 1 |
MF | ME |
| 11/12/2021 15:30 |
(FT) | Leixoes[13] SC Covilha[16] |
2 1 |
0 0 |
MF | ME |
| 12/12/2021 11:00 |
(FT) | SC Farense[14] CD Nacional[6] |
2 2 |
1 0 |
MF | ME |
| 12/12/2021 11:00 |
(FT) | Vilafranquense[15] Porto B[8] |
2 1 |
2 0 |
MF | ME |
| 12/12/2021 14:00 |
(FT) | Academica Coimbra[18] Chaves[9] |
1 2 |
1 1 |
MF | ME |
| 12/12/2021 19:30 |
(FT) | Varzim[17] Clube Desportivo Trofense[10] |
1 3 |
1 2 |
MF | ME |
| 13/12/2021 18:00 |
(FT) | Amadora[12] Casa Pia Ac[2] |
1 0 |
1 0 |
MF | ME |
| 14/12/2021 18:00 |
(FT) | Academico Viseu[11] SL Benfica B[1] |
0 1 |
0 1 |
MF | ME |
| 08/01/2022 14:00 |
(FT) | Chaves[6] Rio Ave[4] |
? ? |
? ? |
MF | ME |
| 12/01/2022 15:30 |
(FT) | Varzim[18] SC Farense[16] |
? ? |
? ? |
MF | ME |