| Time | Status | Match | FT | H1 | Stats |
| 08/04/2022 18:00 |
(FT) | Penafiel[9] Varzim[16] |
4 1 |
0 0 |
MF | ME |
| 09/04/2022 11:00 |
(FT) | Casa Pia Ac[2] SC Farense[10] |
1 0 |
1 0 |
MF | ME |
| 09/04/2022 14:00 |
(FT) | SL Benfica B[5] Amadora[13] |
0 0 |
0 0 |
MF | ME |
| 09/04/2022 14:00 |
(FT) | CD Mafra[8] Chaves[3] |
0 1 |
0 1 |
MF | ME |
| 09/04/2022 15:30 |
(FT) | Vilafranquense[12] Academico Viseu[15] |
2 1 |
0 0 |
MF | ME |
| 10/04/2022 11:00 |
(FT) | SC Covilha[17] Academica Coimbra[18] |
2 0 |
0 0 |
MF | ME |
| 10/04/2022 14:00 |
(FT) | CD Nacional[6] Rio Ave[1] |
2 0 |
0 0 |
MF | ME |
| 10/04/2022 15:30 |
(FT) | Porto B[11] Feirense[4] |
2 1 |
0 1 |
MF | ME |
| 10/04/2022 16:59 |
(FT) | Clube Desportivo Trofense[14] Leixoes[7] |
1 2 |
1 0 |
MF | ME |