| Time | Status | Match | FT | H1 | Stats |
| 21/09/2021 18:30 |
(FT) | Getafe[19] Atletico Madrid[3] |
1 2 |
1 0 |
MF | ME |
| 21/09/2021 21:00 |
(FT) | Athletic Bilbao[5] Rayo Vallecano[13] |
1 2 |
1 1 |
MF | ME |
| 21/09/2021 21:00 |
(FT) | Levante[15] Celta Vigo[18] |
0 2 |
0 0 |
MF | ME |
| 22/09/2021 18:30 |
(FT) | Espanyol[16] Alaves[20] |
1 0 |
0 0 |
MF | ME |
| 22/09/2021 18:30 |
(FT) | Sevilla[7] Valencia[3] |
3 1 |
3 1 |
MF | ME |
| 22/09/2021 21:00 |
(FT) | Real Madrid[2] Mallorca[10] |
6 1 |
3 1 |
MF | ME |
| 22/09/2021 21:00 |
(FT) | Villarreal[15] Elche[11] |
4 1 |
2 1 |
MF | ME |
| 23/09/2021 18:30 |
(FT) | Granada[17] Real Sociedad[4] |
2 3 |
1 0 |
MF | ME |
| 23/09/2021 18:30 |
(FT) | Osasuna[7] Real Betis[11] |
1 3 |
1 1 |
MF | ME |
| 23/09/2021 21:00 |
(FT) | Cadiz[13] Barcelona[10] |
0 0 |
0 0 |
MF | ME |