| Time | Status | Match | FT | H1 | Stats |
| 26/10/2021 18:00 |
(FT) | Alaves[19] Elche[14] |
1 0 |
0 0 |
MF | ME |
| 26/10/2021 20:00 |
(FT) | Espanyol[11] Athletic Bilbao[9] |
1 1 |
1 0 |
MF | ME |
| 26/10/2021 20:30 |
(FT) | Villarreal[12] Cadiz[17] |
3 3 |
1 2 |
MF | ME |
| 27/10/2021 18:00 |
(FT) | Mallorca[12] Sevilla[4] |
1 1 |
1 0 |
MF | ME |
| 27/10/2021 18:00 |
(FT) | Rayo Vallecano[6] Barcelona[8] |
1 0 |
1 0 |
MF | ME |
| 27/10/2021 19:00 |
(FT) | Real Betis[9] Valencia[10] |
4 1 |
2 1 |
MF | ME |
| 27/10/2021 20:30 |
(FT) | Real Madrid[3] Osasuna[2] |
0 0 |
0 0 |
MF | ME |
| 28/10/2021 18:00 |
(FT) | Celta Vigo[15] Real Sociedad[1] |
0 2 |
0 0 |
MF | ME |
| 28/10/2021 19:00 |
(FT) | Granada[16] Getafe[20] |
1 1 |
0 1 |
MF | ME |
| 28/10/2021 20:30 |
(FT) | Levante[19] Atletico Madrid[4] |
2 2 |
1 1 |
MF | ME |