| Time | Status | Match | FT | H1 | Stats |
| 25/09/2021 14:00 |
(FT) | Spezia[14] AC Milan[3] |
1 2 |
0 0 |
MF | ME |
| 25/09/2021 16:59 |
(FT) | Inter Milan[1] Atalanta[4] |
2 2 |
1 2 |
MF | ME |
| 25/09/2021 19:45 |
(FT) | Genoa[13] Hellas Verona[15] |
3 3 |
0 1 |
MF | ME |
| 26/09/2021 11:30 |
(FT) | Juventus[12] Sampdoria[13] |
3 2 |
2 1 |
MF | ME |
| 26/09/2021 14:00 |
(FT) | Empoli[11] Bologna[8] |
4 2 |
2 1 |
MF | ME |
| 26/09/2021 14:00 |
(FT) | US Sassuolo Calcio[16] Salernitana[20] |
1 0 |
0 0 |
MF | ME |
| 26/09/2021 14:00 |
(FT) | Udinese[10] Fiorentina[6] |
0 1 |
0 1 |
MF | ME |
| 26/09/2021 16:59 |
(FT) | Lazio[7] AS Roma[4] |
3 2 |
2 1 |
MF | ME |
| 26/09/2021 19:45 |
(FT) | Napoli[1] Cagliari[19] |
2 0 |
1 0 |
MF | ME |
| 27/09/2021 19:45 |
(FT) | Venezia[18] Torino[9] |
1 1 |
0 0 |
MF | ME |