| Time | Status | Match | FT | H1 | Stats |
| 20/11/2021 14:00 |
(FT) | Atalanta[4] Spezia[16] |
5 2 |
3 1 |
MF | ME |
| 20/11/2021 17:00 |
(FT) | Lazio[5] Juventus[8] |
0 2 |
0 1 |
MF | ME |
| 20/11/2021 19:45 |
(FT) | Fiorentina[7] AC Milan[2] |
4 3 |
2 0 |
MF | ME |
| 21/11/2021 11:30 |
(FT) | US Sassuolo Calcio[13] Cagliari[20] |
2 2 |
1 1 |
MF | ME |
| 21/11/2021 14:00 |
(FT) | Bologna[9] Venezia[15] |
0 1 |
0 0 |
MF | ME |
| 21/11/2021 14:00 |
(FT) | Salernitana[19] Sampdoria[18] |
0 2 |
0 2 |
MF | ME |
| 21/11/2021 17:00 |
(FT) | Inter Milan[3] Napoli[1] |
3 2 |
2 1 |
MF | ME |
| 21/11/2021 19:45 |
(FT) | Genoa[17] AS Roma[6] |
0 2 |
0 0 |
MF | ME |
| 22/11/2021 17:30 |
(FT) | Hellas Verona[10] Empoli[11] |
2 1 |
0 0 |
MF | ME |
| 22/11/2021 19:45 |
(FT) | Torino[12] Udinese[14] |
2 1 |
1 0 |
MF | ME |