| Time | Status | Match | FT | H1 | Stats |
| 04/12/2021 14:00 |
(FT) | AC Milan[2] Salernitana[20] |
2 0 |
2 0 |
MF | ME |
| 04/12/2021 17:00 |
(FT) | AS Roma[5] Inter Milan[3] |
0 3 |
0 3 |
MF | ME |
| 04/12/2021 19:45 |
(FT) | Napoli[1] Atalanta[4] |
2 3 |
1 1 |
MF | ME |
| 05/12/2021 11:30 |
(FT) | Bologna[8] Fiorentina[6] |
2 3 |
1 1 |
MF | ME |
| 05/12/2021 14:00 |
(FT) | Spezia[17] US Sassuolo Calcio[11] |
2 2 |
1 0 |
MF | ME |
| 05/12/2021 14:00 |
(FT) | Venezia[16] Hellas Verona[10] |
3 4 |
3 0 |
MF | ME |
| 05/12/2021 17:00 |
(FT) | Sampdoria[15] Lazio[9] |
1 3 |
0 3 |
MF | ME |
| 05/12/2021 19:45 |
(FT) | Juventus[7] Genoa[18] |
2 0 |
1 0 |
MF | ME |
| 06/12/2021 17:30 |
(FT) | Empoli[11] Udinese[14] |
3 1 |
0 1 |
MF | ME |
| 06/12/2021 19:45 |
(FT) | Cagliari[19] Torino[13] |
1 1 |
0 1 |
MF | ME |