| Time | Status | Match | FT | H1 | Stats |
| 12/09/2021 19:00 |
(FT) | Santiago Wanderers[17] Cobresal[7] |
2 1 |
1 1 |
MF | ME |
| 12/09/2021 21:30 |
(FT) | Audax Italiano[2] Union La Calera[4] |
2 3 |
2 1 |
MF | ME |
| 13/09/2021 00:00 |
(FT) | Curico Unido[16] Univ Catolica[3] |
2 4 |
2 2 |
MF | ME |
| 13/09/2021 20:30 |
(FT) | Nublense[10] Huachipato[14] |
2 2 |
0 2 |
MF | ME |
| 13/09/2021 23:00 |
(FT) | Union Espanola[6] Universidad de Chile[5] |
2 3 |
1 2 |
MF | ME |
| 14/09/2021 18:00 |
(FT) | La Serena[11] O Higgins[12] |
2 0 |
1 0 |
MF | ME |
| 14/09/2021 23:00 |
(FT) | Colo Colo[1] Everton CD[9] |
2 0 |
0 0 |
MF | ME |
| 15/09/2021 20:00 |
(FT) | Palestino[13] Melipilla[15] |
3 1 |
3 1 |
MF | ME |