| Time | Status | Match | FT | H1 | Stats |
| 10/09/2021 20:00 |
(FT) | Sporting de Gijon[1] Leganes[21] |
2 1 |
1 0 |
MF | ME |
| 11/09/2021 15:00 |
(FT) | Real Sociedad B[12] Eibar[18] |
2 3 |
0 1 |
MF | ME |
| 11/09/2021 15:00 |
(FT) | SD Amorebieta[19] Burgos CF[15] |
2 2 |
1 1 |
MF | ME |
| 11/09/2021 17:15 |
(FT) | Las Palmas[13] Ud Ibiza[8] |
1 1 |
0 1 |
MF | ME |
| 11/09/2021 20:00 |
(FT) | CD Mirandes[5] Alcorcon[22] |
1 3 |
1 1 |
MF | ME |
| 12/09/2021 13:00 |
(FT) | Real Oviedo[11] Cartagena[9] |
2 0 |
1 0 |
MF | ME |
| 12/09/2021 15:00 |
(FT) | Valladolid[6] Tenerife[4] |
0 2 |
0 2 |
MF | ME |
| 12/09/2021 17:15 |
(FT) | SD Ponferradina[3] Almeria[2] |
1 0 |
0 0 |
MF | ME |
| 12/09/2021 19:30 |
(FT) | Fuenlabrada[10] Zaragoza[17] |
1 1 |
1 0 |
MF | ME |
| 12/09/2021 20:30 |
(FT) | Malaga[14] Girona[16] |
2 0 |
1 0 |
MF | ME |
| 13/09/2021 20:00 |
(FT) | CD Lugo[20] SD Huesca[7] |
3 2 |
1 2 |
MF | ME |