| Time | Status | Match | FT | H1 | Stats |
| 19/11/2021 20:00 |
(FT) | Fuenlabrada[19] CD Mirandes[17] |
1 1 |
1 0 |
MF | ME |
| 20/11/2021 15:00 |
(FT) | Real Oviedo[12] SD Amorebieta[21] |
2 0 |
2 0 |
MF | ME |
| 20/11/2021 17:15 |
(FT) | Malaga[7] Las Palmas[5] |
2 1 |
1 0 |
MF | ME |
| 20/11/2021 19:30 |
(FT) | Almeria[1] Valladolid[3] |
3 1 |
0 1 |
MF | ME |
| 21/11/2021 13:00 |
(FT) | Cartagena[11] Burgos CF[16] |
1 0 |
0 0 |
MF | ME |
| 21/11/2021 15:00 |
(FT) | CD Lugo[15] Eibar[2] |
2 2 |
2 1 |
MF | ME |
| 21/11/2021 17:15 |
(FT) | SD Huesca[14] Ud Ibiza[9] |
0 0 |
0 0 |
MF | ME |
| 21/11/2021 17:15 |
(FT) | Tenerife[4] Alcorcon[22] |
1 0 |
0 0 |
MF | ME |
| 21/11/2021 19:30 |
(FT) | SD Ponferradina[6] Sporting de Gijon[10] |
4 1 |
3 0 |
MF | ME |
| 22/11/2021 18:00 |
(FT) | Real Sociedad B[18] Girona[13] |
1 2 |
0 1 |
MF | ME |
| 22/11/2021 20:00 |
(FT) | Zaragoza[8] Leganes[20] |
0 2 |
0 1 |
MF | ME |