| Time | Status | Match | FT | H1 | Stats |
| 11/09/2021 15:00 |
(FT) | Albion Rovers[9] Cowdenbeath[8] |
2 1 |
1 1 |
MF | ME |
| 11/09/2021 15:00 |
(FT) | Annan Athletic[2] Stenhousemuir[10] |
1 2 |
0 0 |
MF | ME |
| 11/09/2021 15:00 |
(FT) | Kelty Hearts[1] Elgin City[6] |
1 1 |
0 1 |
MF | ME |
| 11/09/2021 15:00 |
(FT) | Stirling Albion[4] Forfar Athletic[3] |
1 0 |
0 0 |
MF | ME |
| 11/09/2021 15:00 |
(FT) | Stranraer[7] Edinburgh City[5] |
0 1 |
0 0 |
MF | ME |