| Time | Status | Match | FT | H1 | Stats |
| 13/10/2021 21:00 |
(FT) | Cumbaya Pottu via HO |
4 3 |
3 1 |
MF | ME |
| 13/10/2021 21:00 |
(FT) | Chacaritas Sociedad Deportivo Quito |
2 2 |
0 1 |
MF | ME |
| 13/10/2021 21:30 |
(FT) | Gualaceo SC Santo Domingo |
1 0 |
1 0 |
MF | ME |
| 13/10/2021 21:30 |
(FT) | CD Independiente Juniors CD El Nacional |
1 1 |
0 0 |
MF | ME |
| 13/10/2021 21:30 |
(FT) | Buhos ULVR Atletico Porteno |
4 3 |
2 0 |
MF | ME |