| Time | Status | Match | FT | H1 | Stats |
| 22/09/2021 01:00 |
(FT) | Atletico Porteno CD El Nacional |
1 1 |
0 1 |
MF | ME |
| 22/09/2021 19:30 |
(FT) | Pottu via HO Santo Domingo |
3 3 |
3 0 |
MF | ME |
| 22/09/2021 21:00 |
(FT) | Sociedad Deportivo Quito Gualaceo SC |
1 1 |
0 1 |
MF | ME |
| 22/09/2021 21:00 |
(FT) | Chacaritas Buhos ULVR |
4 1 |
2 1 |
MF | ME |
| 24/09/2021 01:00 |
(FT) | Cumbaya CD Independiente Juniors |
2 1 |
2 0 |
MF | ME |