| Time | Status | Match | FT | H1 | Stats | |
| 21/11/2021 01:00 |
(FT) | Santos Laguna[(a)-5] Atletico San Luis[(a)-12] |
2 0 |
0 0 |
MF | ME | |
| 21/11/2021 03:15 |
(FT) | Puebla[(a)-7] Chivas Guadalajara[(a)-10] |
2 2 |
1 1 |
MF | ME | |
| 90 minutes[2-2], Penalty Kicks[4-3] | ||||||
| 21/11/2021 23:00 |
(FT) | Toluca[(a)-6] Pumas UNAM[(a)-11] |
1 2 |
0 1 |
MF | ME | |
| 22/11/2021 01:15 |
(FT) | CDSyC Cruz Azul[(a)-8] Monterrey[(a)-9] |
1 4 |
1 2 |
MF | ME | |