| Time | Status | Match | FT | H1 | Stats |
| 22/10/2021 17:30 |
(FT) | Torino[12] Genoa[18] |
3 2 |
2 0 |
MF | ME |
| 22/10/2021 19:45 |
(FT) | Sampdoria[17] Spezia[16] |
2 1 |
2 0 |
MF | ME |
| 23/10/2021 14:00 |
(FT) | Salernitana[20] Empoli[11] |
2 4 |
0 4 |
MF | ME |
| 23/10/2021 16:59 |
(FT) | US Sassuolo Calcio[14] Venezia[15] |
3 1 |
1 1 |
MF | ME |
| 23/10/2021 19:45 |
(FT) | Bologna[8] AC Milan[2] |
2 4 |
0 2 |
MF | ME |
| 24/10/2021 11:30 |
(FT) | Atalanta[6] Udinese[10] |
1 1 |
0 0 |
MF | ME |
| 24/10/2021 14:00 |
(FT) | Fiorentina[9] Cagliari[19] |
3 0 |
2 0 |
MF | ME |
| 24/10/2021 14:00 |
(FT) | Hellas Verona[13] Lazio[5] |
4 1 |
2 0 |
MF | ME |
| 24/10/2021 16:59 |
(FT) | AS Roma[4] Napoli[1] |
0 0 |
0 0 |
MF | ME |
| 24/10/2021 19:45 |
(FT) | Inter Milan[3] Juventus[7] |
1 1 |
1 0 |
MF | ME |