| Time | Status | Match | FT | H1 | Stats |
| 11/09/2021 15:00 |
(FT) | Alfreton Town[20] AFC Telford United[16] |
3 1 |
1 0 |
MF | ME |
| 11/09/2021 15:00 |
(FT) | Blyth Spartans[8] Darlington[22] |
2 2 |
2 1 |
MF | ME |
| 11/09/2021 15:00 |
(FT) | Brackley Town[2] Southport FC[19] |
1 0 |
1 0 |
MF | ME |
| 11/09/2021 15:00 |
(FT) | Bradford Park Avenue[17] AFC Fylde[1] |
0 2 |
0 0 |
MF | ME |
| 11/09/2021 15:00 |
(FT) | Chorley[9] Chester FC[15] |
4 1 |
3 1 |
MF | ME |
| 11/09/2021 15:00 |
(FT) | Gloucester City[18] Curzon Ashton[4] |
1 2 |
1 1 |
MF | ME |
| 11/09/2021 15:00 |
(FT) | Guiseley[14] Kettering Town[7] |
0 2 |
0 0 |
MF | ME |
| 11/09/2021 15:00 |
(FT) | Kidderminster[3] Gateshead[6] |
2 3 |
1 2 |
MF | ME |
| 11/09/2021 15:00 |
(FT) | Leamington[13] Boston United[10] |
2 0 |
0 0 |
MF | ME |
| 11/09/2021 15:00 |
(FT) | Spennymoor Town[5] Farsley Celtic[11] |
6 0 |
3 0 |
MF | ME |
| 25/09/2021 15:00 |
(FT) | Southport FC[21] Chorley[8] |
? ? |
? ? |
MF | ME |
| 28/09/2021 19:45 |
(FT) | York City[11] Hereford[22] |
0 1 |
0 0 |
MF | ME |