| Time | Status | Match | FT | H1 | Stats |
| 28/01/2022 19:45 |
(FT) | Bala Town[7] Newtown[2] |
1 0 |
1 0 |
MF | ME |
| 28/01/2022 19:45 |
(FT) | Caernarfon[6] The New Saints[1] |
0 4 |
0 1 |
MF | ME |
| 28/01/2022 19:45 |
(FT) | Haverfordwest County[10] Penybont[4] |
2 2 |
1 2 |
MF | ME |
| 28/01/2022 20:00 |
(FT) | Aberystwyth Town[11] Newi Cefn Druids[12] |
5 0 |
3 0 |
MF | ME |
| 29/01/2022 14:30 |
(FT) | Connah's QN[5] Barry Town Afc[9] |
2 3 |
1 0 |
MF | ME |
| 29/01/2022 14:30 |
(FT) | Flint Town United[3] Cardiff Metropolitan[8] |
2 2 |
2 1 |
MF | ME |