| Time | Status | Match | FT | H1 | Stats |
| 23/10/2021 11:30 |
(FT) | Humenne[2] Dukla Banska Bystrica[1] |
1 1 |
0 1 |
MF | ME |
| 23/10/2021 13:00 |
(FT) | Slovan Bratislava B[15] Mfk Skalica[5] |
1 2 |
1 0 |
MF | ME |
| 23/10/2021 13:30 |
(FT) | Partizan Bardejov[14] Sport Podbrezova[4] |
0 2 |
0 1 |
MF | ME |
| 23/10/2021 13:30 |
(FT) | Slavoj Trebisov[10] SKM Puchov[13] |
2 1 |
0 1 |
MF | ME |
| 23/10/2021 13:30 |
(FT) | Msk Zilina B[9] MFK Kosice[6] |
3 2 |
1 1 |
MF | ME |
| 24/10/2021 09:30 |
(FT) | Artmedia Petrzalka[6] KFC Komarno[3] |
2 2 |
1 0 |
MF | ME |
| 24/10/2021 10:00 |
(FT) | Rohoznik[11] Namestovo[16] |
2 1 |
2 1 |
MF | ME |
| 25/10/2021 13:30 |
(FT) | Mfk Nova Dubnica[12] Stk 1914 Samorin[8] |
1 2 |
1 0 |
MF | ME |