| Time | Status | Match | FT | H1 | Stats |
| 20/09/2021 19:30 |
(FT) | Frosinone[7] Brescia[1] |
2 2 |
2 1 |
MF | ME |
| 21/09/2021 16:59 |
(FT) | Benevento[11] Cittadella[7] |
4 1 |
1 1 |
MF | ME |
| 21/09/2021 16:59 |
(FT) | Alessandria[18] Ascoli[3] |
1 3 |
0 2 |
MF | ME |
| 21/09/2021 19:30 |
(FT) | Crotone[13] Lecce[16] |
0 3 |
0 2 |
MF | ME |
| 21/09/2021 19:30 |
(FT) | Pordenone[20] Reggina[8] |
1 1 |
1 0 |
MF | ME |
| 21/09/2021 19:30 |
(FT) | Pisa[2] Ac Monza[9] |
2 1 |
1 0 |
MF | ME |
| 21/09/2021 19:30 |
(FT) | Spal[10] Vicenza[17] |
3 2 |
1 1 |
MF | ME |
| 21/09/2021 19:30 |
(FT) | Cosenza[14] Como[15] |
2 0 |
1 0 |
MF | ME |
| 22/09/2021 16:59 |
(FT) | Ternana[17] Parma[7] |
3 1 |
0 0 |
MF | ME |
| 22/09/2021 19:30 |
(FT) | Cremonese[9] Perugia[11] |
0 3 |
0 2 |
MF | ME |