| Time | Status | Match | FT | H1 | Stats |
| 11/12/2021 15:00 |
(FT) | Crewe Alexandra[23] Sheffield Wed[8] |
0 2 |
0 1 |
MF | ME |
| 11/12/2021 15:00 |
(FT) | Wigan Athletic[4] Ipswich[11] |
1 1 |
1 0 |
MF | ME |
| 11/12/2021 15:00 |
(FT) | Accrington Stanley[13] Bolton Wanderers[16] |
1 0 |
1 0 |
MF | ME |
| 11/12/2021 15:00 |
(FT) | Fleetwood Town[21] Gillingham[22] |
2 1 |
1 0 |
MF | ME |
| 11/12/2021 15:00 |
(FT) | Doncaster Rovers[24] Shrewsbury Town[19] |
1 0 |
0 0 |
MF | ME |
| 11/12/2021 15:00 |
(FT) | Wycombe Wanderers[2] AFC Wimbledon[17] |
2 2 |
0 1 |
MF | ME |
| 11/12/2021 15:00 |
(FT) | Sunderland[3] Plymouth Argyle[6] |
2 1 |
2 0 |
MF | ME |
| 11/12/2021 15:00 |
(FT) | Milton Keynes Dons[7] Oxford United[5] |
1 2 |
1 0 |
MF | ME |
| 11/12/2021 15:00 |
(FT) | Charlton Athletic[14] Cambridge United[15] |
2 0 |
1 0 |
MF | ME |
| 11/12/2021 15:00 |
(FT) | Rotherham United[1] Burton Albion FC[10] |
3 1 |
1 1 |
MF | ME |
| 11/12/2021 15:00 |
(FT) | Portsmouth[9] Morecambe[20] |
2 0 |
1 0 |
MF | ME |
| 11/12/2021 15:00 |
(FT) | Cheltenham Town[12] Lincoln City[18] |
2 2 |
1 0 |
MF | ME |