| Time | Status | Match | FT | H1 | Stats |
| 03/05/2022 19:30 |
(FT) | CD El Nacional Imbabura Sc |
2 4 |
2 2 |
MF | ME |
| 03/05/2022 21:00 |
(FT) | Buhos ULVR[8] Sociedad Deportivo Quito[4] |
3 2 |
2 1 |
MF | ME |
| 05/05/2022 01:00 |
(FT) | Manta Chacaritas |
1 1 |
1 0 |
MF | ME |
| 05/05/2022 21:00 |
(FT) | Santo Domingo[9] Olmedo Riobamba[7] |
1 2 |
0 1 |
MF | ME |
| 06/05/2022 01:00 |
(FT) | Libertad Asuncion[5] CD Independiente Juniors[3] |
1 0 |
0 0 |
MF | ME |