| Minute | Score | Mainz 05 | Bayer Leverkusen | |
| 4' | 0 - 0 |  Xhaka G. |
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| 18' | 0 - 1 |  van den Berg S. (Own goal) |
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| 58' | 0 - 1 | Fernandes E. |
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| 59' | 0 - 2 | Grimaldo A. |
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| 63' | 0 - 2 |  Adli A. (Wirtz F.) |
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| 65' | 0 - 3 | Hofmann J. (Adli A.) |
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| 69' | 0 - 3 | El-Ghazi A. (da Costa D.) |
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| 69' | 0 - 3 | Barkok A. (Lee Jae-Sung) |
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| 70' | 0 - 3 | Krauss T. (Kohr D.) |
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| 75' | 0 - 3 | Gruda B. |
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| 76' | 0 - 3 | Ajorque L. (Gruda B.) |
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| 79' | 0 - 3 | Hlozek A. (Boniface V.) |
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| 79' | 0 - 3 | Andrich R. (Xhaka G.) |
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| 84' | 0 - 3 | Richter M. (Onisiwo K.) |
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| 86' | 0 - 3 | Amiri N. (Hofmann J.) |
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| 86' | 0 - 3 | Stanisic J. (Frimpong J.) |
